Pour chicken broth into bottom of pressure cooker. Season both sides of chicken breast with salt and pepper.
Spread pesto over both sides of chicken and add to bottom of the pot. Close the valve to the sealed position. Select high pressure for 4 minutes if using fresh chicken, 10 minutes if using frozen chicken. *For two pounds of chicken select 5 minutes.
Allow to naturally release for 10 minutes. Then switch valve to open, being cautious to allow steam out if need. Open the lid and check temperature of chicken has reach 160F.